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Main content
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New
Glycerin 22 Running Shoe video
(644)644

Glycerin 22 Running Shoe

Brooks

Men

$99.97Current Price $99.97
(39% off)39% off.
$165.00Comparable value $165.00
Color
Color: Primer Gray Ebony Bluewash
12.5
D
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Details & care

Engineered for soft landing and explosive toe-offs, this lightweight running shoe sits on nitrogen-infused cushioning and a broad-platform sole that promotes smooth heel-to-toe transitions.

Perfect for: Runners of all levels looking to ground every stride with lightweight cushioning, springy energy and grippy confidence.

Upper: Air Mesh stretches and recovers with the movement of every stride while providing essential ventilation. Double-jacquard knit ensures a more accommodating fit from your first stride to your last.

Midsole Drop: 10mm, the most common and generally considered to be the ideal standard for running shoes. Classified as a high-drop measurement, it allows for more cushioning to absorb the impact of heel strikes.

Lower: DNA Tuned nitrogen-infused foam transitions from large, impact-absorbing cells in the heel to small, energy-responsive cells under the toe. Broad platform stabilizes your stride and provides confident heel-to-toe movement. RoadTack Rubber puts targeted traction and springy rebound in high-wear areas of the tread.

  • Cushioning: absorbs impact and distributes weight for consistent, buoyant comfort under each step
  • Energy return: transforms every heel strike into responsive, explosive forward movement
  • Stability: helps maintain comfortable foot alignment with targeted cushioning and support
  • Lace-up style
  • Air Mesh upper fuses stretchy comfort with ultralightweight breathability
  • Removable, cushioned insole allows for custom orthotics
  • DNA Tuned nitrogen-infused foam transitions each stride from airy landings to turbocharged toe-offs
  • RoadTack Rubber tread partially made with recycled materials puts lightweight durability and rebound under every stride
  • Textile and synthetic upper and lining/rubber and synthetic sole
  • Imported
  • Item #10428452
  • Core Product ID 333333GVKQ

Size info

  • If between sizes, order next 1/2 size up.

Shipping & returns

This item qualifies for free shipping on orders over $89. View Shipping & Returns Policy.

This item is returnable within 40 days by mail or to U.S. Nordstrom Rack and U.S. Nordstrom stores. All beauty items are only eligible for return in U.S. Nordstrom Rack or U.S. Nordstrom stores.

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Brooks

Brooks was founded in 1914 in Philadelphia before moving to Seattle, where the company is headquartered today. Brooks running shoes are designed with specialized high-tech features like DNA midsoles for adaptive cushioning and 3D Fit Print for lightweight, flexible structure. The brand also offers running clothing to make sure you're fully outfitted for any run.

Reviews

(644)6444.5 out of 5
Write a Review

Most helpful positive review

Apr 13, 2026

Lightweight and stable

[This review was collected as part of a promotion.] The Glycerin 22s were my first pair of Brooks running shoes after being a lifelong New Balance user. I have used my Glycerin 22s for the past 3+ months for all of my road runs of between 3-9 miles and I have been so happy with them I am looking forward to my next pair of Glycerin's when the time comes. Overall, the fit is consistent with other running shoes, I sized up a whole size (I wear a 9.5 in dress shoes and 10.5 in running shoes). The shoes are light but have sufficient support that I don't feel like there is a compromise in the stability of the shoe in exchange for weight. Also, I really like the laces. The laces are lightweight but also feel like they hold up really well during runs. All together, I love the Glycerin 22s!
BernardoM

Most helpful critical review

Feb 21, 2026

Possibly defective

I don't know if I got a defective pair or what but these hurt my feet on day 1. My left foot specifically on the outer side, but not the right side. These seem a bit narrow in the middle and I bought wide. I ususally wear ghost or ghost max but wanted to try something different because the quality of Brooks shoes has seemingly gotten worse every year over the past 5 years. I've seen many others long term brooks users complaining about the quality as well. I thought I would wear brooks for the rest of my life when I first tried them on 9 years ago but I don't know anymore.
KevinV

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5 stars74%
4 stars11%
3 stars6%
2 stars4%
1 star4%
Apr 13, 2026

Lightweight and stable

[This review was collected as part of a promotion.] The Glycerin 22s were my first pair of Brooks running shoes after being a lifelong New Balance user. I have used my Glycerin 22s for the past 3+ months for all of my road runs of between 3-9 miles and I have been so happy with them I am looking forward to my next pair of Glycerin's when the time comes. Overall, the fit is consistent with other running shoes, I sized up a whole size (I wear a 9.5 in dress shoes and 10.5 in running shoes). The shoes are light but have sufficient support that I don't feel like there is a compromise in the stability of the shoe in exchange for weight. Also, I really like the laces. The laces are lightweight but also feel like they hold up really well during runs. All together, I love the Glycerin 22s!
BernardoM
Mar 13, 2026

The Glycerine 22 is my favorite running shoe

[This review was collected as part of a promotion.] The Brooks Glycerine 22 is my favorite running and walking shoe because it’s comfortable enough to wear all day and provides great support and cushioning.
Howardw
Mar 13, 2026

Great Shoes!

[This review was collected as part of a promotion.] I love the Brooks Glycerin 22! The cushioning is soft and comfortable without feeling unstable. They’re great for both running and walking. They fit true to size. I would definitely buy them again.
MelissaS
Mar 13, 2026

Go to a store first to make sure of size

[This review was collected as part of a promotion.] This shoe didn't fit the same way as my 1st pair, both the same size but not the same fit. My feet feel sore and tired by the end of a work day I do like the cushion and shoe just need to probably get different size
RobertR
Mar 13, 2026

First few weeks

[This review was collected as part of a promotion.] At first was not sure about these, but after wearing few time these are really nice. Do a lot of walking and these really feel great.
JohnF
Mar 12, 2026

The best walking shoe

[This review was collected as part of a promotion.] A clear winner. I walk a lot at trade shows, and I have tried many of the other top brands that claim their shoes are good for walking, but the Brooks Glycerin 22 is clearly my go-to from now on. I have 4 pairs
DanielA
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    New
    Vans
    $129.97Current Price $129.97
    (44% off)44% off.
    $235.00Comparable value $235.00
  • Comfycush Old Skool Sneaker
    New
    Vans
    $69.97Current Price $69.97
    (45% off)45% off.
    $128.00Comparable value $128.00
  • Hightrail Waterproof Hiking Shoe
    New
    KEEN
    $79.97Current Price $79.97
    (46% off)46% off.
    $150.00Comparable value $150.00
  • Altamesa 300 Trail Running Shoe
    New
    The North Face
    $79.97Current Price $79.97
    (38% off)38% off.
    $129.00Comparable value $129.00
  • ST329 CMF Sneaker
    New
    K-Swiss
    Add to Bag or Wish List to see price(24)
  • Classic 88 x Engineered Garments Leather Sneaker
    New
    K-Swiss
    $29.97Current Price $29.97
    (73% off)73% off.
    $115.00Comparable value $115.00
  • Old Skool Two-Tone Sneaker
    New
    Vans
    $39.97Current Price $39.97
    (42% off)42% off.
    $70.00Comparable value $70.00
  • Old Skool Leather Sneaker
    New
    Vans
    $39.97Current Price $39.97
    (42% off)42% off.
    $70.00Comparable value $70.00
    (3)
  • Melrose Tubes Lite Sneaker
    New
    K-Swiss
    $29.97 – $39.97Current Price $29.97 to $39.97
    (Up to 62% off)Up to 62% off.
    $80.00Comparable value $80.00
    (6)
  • GEL-DS TRAINER 14 Sneaker
    Popular
    New
    ASICS®
    $89.97Current Price $89.97
    (Up to 25% off)Up to 25% off.
    $110.00 – $120.00Comparable value $110.00 to $120.00
  • Grand Crosscourt Packaway Leather Sneaker
    New
    Cole Haan
    $99.97Current Price $99.97
    (39% off)39% off.
    $165.00Comparable value $165.00
  • Air Winflo 12 Running Shoe
    Popular
    New
    Nike
    Add to Bag or Wish List to see price(5)
  • SI-18 International Sneaker
    New
    K-Swiss
    $64.97 – $69.97Current Price $64.97 to $69.97
    (Up to 48% off)Up to 48% off.
    $125.00Comparable value $125.00
  • Superstar X Marcos Leather Sneaker
    New
    adidas
    $69.97Current Price $69.97
    (36% off)36% off.
    $110.00Comparable value $110.00
  • Viator Mesh Sneaker
    New
    Propét
    $54.97Current Price $54.97
    (53% off)53% off.
    $117.49Comparable value $117.49
  • Primera Sneaker
    New
    Magnanni
    $249.97Current Price $249.97
    (47% off)47% off.
    $475.00Comparable value $475.00
  • Trailfly Speed V2 Trail Running Shoe
    New
    INOV8 FOOTWEAR
    $129.97Current Price $129.97
    (25% off)25% off.
    $175.00Comparable value $175.00
  • Sprint Anthem Sneaker
    New
    Merrell
    $79.97Current Price $79.97
    (20% off)20% off.
    $100.00Comparable value $100.00
    (1)
  • SwiftFit Go Walk Now Walking Shoe
    New
    SKECHERS
    $59.97Current Price $59.97
    (33% off)33% off.
    $90.00Comparable value $90.00
  • G/18 Embossed Skull & Tees Golf Shoe
    New
    G/FORE
    $99.97Current Price $99.97
    (60% off)60% off.
    $250.00Comparable value $250.00
See More
Nordy Club member exclusive! Enter monthly for a chance to win a $100 promo card. Sweepstakes ends October 31.Nordy Club member exclusive! Enter monthly for a chance to win a $100 promo card. Sweepstakes ends October 31.

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Apply today: get $40 off your next purchase plus an extra five percent off for cardmembers. A hand holding a credit card.Apply today: get $40 off your next purchase plus an extra five percent off for cardmembers. A hand holding a credit card.

$40 Off Your Next Purchase

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