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Brooks Glycerin 22 Running Shoe, Main, color,
Brooks Glycerin 22 Running Shoe, Alternate, color,
Glycerin 22 Running Shoe, sales video thumbnail
Brooks Glycerin 22 Running Shoe, Alternate, color,
Brooks Glycerin 22 Running Shoe, Alternate, color,
Brooks Glycerin 22 Running Shoe, Alternate, color,

Glycerin 22 Running Shoe (Women)

Brooks

Women

SOLD OUT

This item is no longer available. Browse our recommendations for something similar.

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Details & care

Engineered for soft landing and explosive toe-offs, this lightweight running shoe sits on nitrogen-infused cushioning and a broad-platform sole that promotes smooth heel-to-toe transitions.

Perfect for: Runners of all levels looking to ground every stride with lightweight cushioning, springy energy and grippy confidence.

Upper: Air Mesh stretches and recovers with the movement of every stride while providing essential ventilation. Double-jacquard knit ensures a more accommodating fit from your first stride to your last.

Midsole Drop: 10mm, the most common and generally considered to be the ideal standard for running shoes. Classified as a high-drop measurement, it allows for more cushioning to absorb the impact of heel strikes.

Lower: DNA Tuned nitrogen-infused foam transitions from large, impact-absorbing cells in the heel to small, energy-responsive cells under the toe. Broad platform stabilizes your stride and provides confident heel-to-toe movement. RoadTack Rubber puts targeted traction and springy rebound in high-wear areas of the tread.

  • Cushioning: absorbs impact and distributes weight for consistent, buoyant comfort under each step
  • Energy return: transforms every heel strike into responsive, explosive forward movement
  • Stability: helps maintain comfortable foot alignment with targeted cushioning and support
  • Lace-up style
  • Air Mesh upper fuses stretchy comfort with ultralightweight breathability
  • Removable, cushioned insole allows for custom orthotics
  • DNA Tuned nitrogen-infused foam transitions each stride from airy landings to turbocharged toe-offs
  • RoadTack Rubber tread partially made with recycled materials puts lightweight durability and rebound under every stride
  • Textile and synthetic upper and lining/rubber and synthetic sole
  • Imported
  • Item #10427182

Size info

  • True to size.

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Brooks

Brooks was founded in 1914 in Philadelphia before moving to Seattle, where the company is headquartered today. Brooks running shoes are designed with specialized high-tech features like DNA midsoles for adaptive cushioning and 3D Fit Print for lightweight, flexible structure. The brand also offers running clothing to make sure you're fully outfitted for any run.

Reviews

(1187)
4.2 out of 5
Write a Review

Most helpful positive review

Apr 11, 2026
Great for more than running
[This review was collected as part of a promotion.] I use these for Step Aerobics and they are by far my favorite runner! Excellent support, light weight, and ohhh so cushie!
StephanieR
Reposted from brooksrunning.com

Most helpful critical review

Mar 31, 2026
[This review was collected as part of a promotion.] I have never had a pair of Brooks I didn't like until this pair. I honestly think it is something with just this pair, the right shoe has something that isn't right and rubs so I will be returning.
LoriW
Reposted from brooksrunning.com

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Sort by Most Helpful
StephanieR
Reposted from brooksrunning.com
Apr 11, 2026
Great for more than running
[This review was collected as part of a promotion.] I use these for Step Aerobics and they are by far my favorite runner! Excellent support, light weight, and ohhh so cushie!
LoriW
Reposted from brooksrunning.com
Mar 31, 2026
[This review was collected as part of a promotion.] I have never had a pair of Brooks I didn't like until this pair. I honestly think it is something with just this pair, the right shoe has something that isn't right and rubs so I will be returning.
ErinM
Reposted from brooksrunning.com
Mar 18, 2026
Great Shoe!
[This review was collected as part of a promotion.] The shoe fits great and is true to size. The soul provides a lot of cushion while walking. The only thing I don’t particularly care for is the tongue on the shoe is quite thick.
PattyM
Reposted from brooksrunning.com
Mar 17, 2026
[This review was collected as part of a promotion.] As soon as I first tried them on I wore them all day into the evening. They are extremely supportive but very comfortable. I’m very happy with them. Plus I love the color.
JeannieM
Reposted from brooksrunning.com
Mar 16, 2026
[This review was collected as part of a promotion.] They are not as comfortable as the 21’s. And I don’t like the area around the inside ankle
AnneJS
Reposted from brooksrunning.com
Mar 16, 2026
Light color
[This review was collected as part of a promotion.] Color is very light, almost white, so I returned them. I’d like some vibrant colors. I already have 3 if the bright Disney collection for color and fun.
Load 6 more reviews
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